Some stroke survivors label fatigue as their greatest obstacle to recovery. It can often limit one’s ability to participate in rehab activities, and promote inactivity and subsequent “learned non-use” of the involved arm or leg. The causes of fatigue after a stroke can be many, and research is ongoing to discover and counteract the primary causative factors. Likely contributing factors are: all daily activities and movements require increased oxygen consumption after a stroke, disruptions in the sleep-wake cycle, sleep-disordered breathing, stress causing sustained excessive releases of hormones (corticotrophin and ACTH) which can lead to symptoms of depression and fatigue, effects of some medications like anticonvulsants and pain meds.
Many stroke survivors will lose motivation to participate in activity because of the increased energy expenditure required, the fear of falling, embarrassment about the appearance of their movements, and other factors. A snowball effect ensues, in which the decreased activity causes further decline in endurance and strength, which makes any activity more difficult, awkward, and filled with fear of falling.